Intracranial Hemorrhage Caused by Vitamin K Deficiency Beyond Neonatal Period

Massive neonatal intracranial hemorrhage caused by bromadiolone

RATIONALE Bromadiolone, often called a super-warfarin, is a potent rodenticide with long half-life. Skin and mucosal bleeding is the most common clinical manifestations of its intoxication. Bromadiolone intoxications in adults and children have been reported, but this phenomenon is rarely seen in fetuses. This paper presents a case of neonate with massive intracranial hemorrhage mediated by bro...

Purpura Caused by Vitamin K Deficiency

Vitamin K Deficiency Bleeding: A Case Revealed by Intracranial Haemorrhage

Intracranial haemorrhage in early childhood is associated with a wide variety of causes such as trauma, vascular malformations (aneurysm and arteriovenous malformation), haemorrhagic infarction, brain tumours or blood coagulation disorders (congenital or acquired from coagulation factors). Vitamin K deficiency causes blood coagulation disturbances that can lead to intracranial haemorrhage [1]. ...

Intracranial Hemorrhage Caused by Non-Vitamin K Antagonist Oral Anticoagulants (NOACs)- Multicenter Retrospective Cohort Study in Japan.

BACKGROUND We conducted a multicenter retrospective cohort study to elucidate the characteristics of intracranial hemorrhage (ICH) in patients with atrial fibrillation treated with non-vitamin K antagonist oral anticoagulants (NOACs). METHOD AND RESULTS We sent a questionnaire to the directors of 241 stroke centers in Japan to establish the clinical characteristics of NOAC-associated cerebral...

Intracranial Haemorrhage Due to Late-Onset Vitamin K Deficiency

Objective: Deficiency of vitamin K predisposes to bleeding and it can be divided into early, classical, or late vitamin K deficiency bleeding (VKDB) according to their onset. Late VKDB occurs after 7th day of life at neonatal period and is associated with intracranial bleeding, serious neurological sequels and death. This retrospective study reviewed the clinical presentations, demographic feat...